He lāʻau bactericidal ākea ʻo Enrofloxacin no nā holoholona ma ka papa flurofenolone. ʻO Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Portella septicarum He hopena maikaʻi kona i nā bacteria, Staphylococcus aureus, mycoplasma, chlamydia, a pēlā aku, akā he hopena nāwaliwali kona i nā Pseudomonas aeruginosa a me Streptococcus a he hopena nāwaliwali hoʻi i nā bacteria anaerobic. Loaʻa iā ia ka hopena antibacterial maopopo ma nā bacteria koʻikoʻi.

Hoʻopili koke ʻia kēia huahana e ka inikini intramuscular. ʻO ka bioavailability o kēia huahana he 91.9% i loko o nā puaʻa a me 82% i loko o nā bipi waiū. Hoʻolaha nui ʻia i loko o nā holoholona a hiki ke komo maʻalahi i nā ʻiʻo a me nā wai o ke kino. Koe wale nō ka wai cerebrospinal, ʻoi aku ka nui o ka lāʻau lapaʻau ma ka hapa nui o nā ʻiʻo ma mua o ke koko. Pulp. ʻO ka metabolism o ke akepaʻa e pili ana i ka wehe ʻana o ka hui ethyl o ke apo 7-crosin e hana i ka ciprofloxacin, ukali ʻia e ka oxidation a me ka glucuronic acid conjugation, i hoʻokuʻu nui ʻia ma o nā puʻupaʻa (ma o ka renal tubular secretion a me ka glomerular filtration), 15% a 50% Hoʻokuʻu ʻia i loko o ka mimi. Hoʻopau i ka hapalua ʻOkoʻa loa ke ola ma nā ʻano holoholona like ʻole a me nā ala like ʻole o ka lawelawe ʻana. ʻO ka hoʻopau ʻana i ka hapalua ola ma hope o ka inikini intramuscular.

nā pilina lāʻau lapaʻau: (1) Loaʻa i kēia huahana kahi hopena synergistic ke hui pū ʻia me nā amino sugars a i ʻole ka penicillin ākea. (2) Hiki i nā ion metala kaumaha e like me Ca2+, Mg2+, Fe; a me Al Children ke launa pū me kēia huahana a hoʻopilikia i ka omo ʻana. (3) Ke hoʻohana ʻia me ka theophylline a me ka caffeine, hiki ke hoʻemi ʻia ka nui o ka hoʻopaʻa ʻana o ka protein plasma, e piʻi aʻe ka nui o ka theophylline a me ka caffeine i loko o ke koko, a hiki ke loaʻa nā hōʻailona o ka lāʻau make theophylline. (4) Loaʻa i kēia huahana ka hopena o ka pale ʻana i nā enzymes lāʻau lapaʻau o ke akepaʻa a hiki ke hoʻemi i ka nui o ka hoʻomaʻemaʻe ʻana o nā lāʻau lapaʻau i hoʻoheheʻe nui ʻia i loko o ke akepaʻa.

Hana a me ka hoʻohana: Nā lāʻau antibiotic Flufenolone. Hoʻohana ʻia no nā maʻi bacteria a me nā maʻi mycoplasma i nā holoholona a me nā manu.